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Your Gut and Your Hormones: Meet the Estrobolome

Of all the hormone connections worth knowing, this one surprises people the most: a chunk of your oestrogen balance is managed in your gut.

Here's the elegant bit. Your liver packages up oestrogen the body has used and sends it toward the gut to be excreted. But a particular set of gut bacteria, collectively nicknamed the estrobolome, produces an enzyme that can "unpackage" some of that oestrogen, allowing it to be reabsorbed back into circulation instead of leaving the body. In other words, your gut bacteria help fine-tune how much oestrogen stays active.

When your gut microbiome is diverse and healthy, this system tends to keep oestrogen in a reasonable balance. When it's disrupted, by a poor diet, certain illnesses or medications, or low fibre, the estrobolome can push oestrogen levels up or down in ways that may contribute to symptoms. Researchers are still mapping exactly how much this matters for conditions women care about, but the link between gut health and hormone balance is real and increasingly well documented.

The practical upshot is reassuringly ordinary, no special protocol required:

You don't need to obsess over your microbiome or buy anything fancy. The same plant-rich, fibre-forward eating that's good for the rest of you happens to support the bacteria quietly helping to manage your hormones. Biology, occasionally, is tidy.

Quick answers

What is the estrobolome?

It's the community of gut bacteria that helps regulate how much oestrogen stays active in your body, by influencing whether used oestrogen is excreted or reabsorbed.

How do I support my gut for hormone balance?

Eat plenty of fibre and a wide variety of plants, include fermented foods if they suit you, and limit ultra-processed food and excess alcohol.

Related reading: Eating for your hormones · Estrogen dominance, explained · Take the free Hormone Quiz

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