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Dong Quai

The traditional 'female ginseng' — but the single-herb capsules sold in the West lack good evidence and carry real blood-thinning cautions.

Dose
When to take
Pairs well with
Avoid
Side effects

The claim

Dong quai (Angelica sinensis), sometimes called 'female ginseng', is one of the most famous herbs in traditional Chinese medicine for women — sold for menstrual cramps, irregular cycles, PMS and menopausal hot flushes.

The 'female ginseng' reputation

Dong quai has been used in Chinese medicine for over a thousand years, almost always as part of a multi-herb formula rather than alone — a detail that matters, because its traditional use and the way it's sold in the West (as a single-herb capsule) are quite different things. Its nickname and long history give it real cultural weight, which is why it deserves an honest look.

What the evidence actually says

The Western trial evidence is disappointing. The most-cited study — a randomised trial of dong quai alone for menopausal hot flushes — found it no better than placebo. Used by itself, there's little good evidence it helps hot flushes, cycles or PMS. Defenders argue this is unfair because dong quai was never traditionally used alone, and some combination-formula studies look more promising — a reasonable point, but it means the single-herb capsules most people buy are the least-supported form.

The safety issues that genuinely matter

Dong quai is one to be careful with. It can thin the blood and has a documented interaction with warfarin (raising bleeding risk), so it shouldn't be combined with anticoagulants. It also contains compounds that can increase photosensitivity (easier sunburn). It should be avoided in pregnancy (it may stimulate the uterus) and around surgery. For a herb often assumed to be gently 'natural', the interaction profile is not trivial.

The hormone question

Despite the 'female' branding, dong quai's effect on oestrogen is unclear and inconsistent in studies — so, like several herbs here, the hormonal framing outruns the evidence.

Better-evidenced alternatives

For period pain, omega-3 and magnesium; for menopausal symptoms, soy isoflavones or (medically) HRT; for PMS mood, saffron or vitex.

Bottom line

Dong quai is a culturally important herb whose single-herb Western form has little good evidence for cycles, PMS or hot flushes — and it carries real blood-thinning, sun-sensitivity and pregnancy cautions. Avoid with anticoagulants and in pregnancy. Better-evidenced options exist. Use only with medical input.

Chapter 12 · Menopause
If you'd like to try it

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Based on guidance from the NHS, NICE, Cleveland Clinic and peer-reviewed research.

By M. Videika, author of The Testosterone Blueprint · Reviewed June 2026

General information, not a substitute for personal medical advice — always consult your doctor or a qualified health professional before making health decisions. If you are pregnant, breastfeeding, trying to conceive, under 18, or taking medication, speak to your doctor before starting any supplement.