The Testosterone Blueprint
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Creatine Monohydrate

The most-researched supplement in sport — it builds the muscle and training capacity that support healthy hormones, rather than raising testosterone directly.

Dose
3–5 g/day monohydrate · No loading needed · No formal upper limit at this dose
When to take
Any time — consistency matters more than timing · Daily, including rest days
Pairs well with
Protein; Magnesium; pairs with almost everything
Avoid
Nothing of note; check with a doctor if you have kidney disease
Side effects
Minor water retention early on; stomach upset if too much at once

What creatine does

Creatine helps regenerate ATP, the body's rapid energy currency, letting you train harder and recover faster. Over time that means more lean muscle, better strength and improved body composition — all of which support a healthier hormonal environment. It also supports brain energy, and it's the most-studied, most reliably effective supplement in sport.

Does creatine raise testosterone?

Mostly indirectly. In one small study, testosterone itself did not change, but DHT — a more potent androgen — rose 56% during a 7-day loading phase and stayed about 40% above baseline through two weeks of maintenance. That single finding fuelled the 'creatine causes hair loss' idea, but no subsequent research has replicated it, and creatine works through energy metabolism rather than hormonal manipulation. The practical truth: creatine's value is in the muscle and performance it builds, not in moving testosterone.

What it does for training

More reps at a given weight, better high-intensity output, faster recovery between sets, and steadier strength progress — especially with resistance training. This benefit is real and well-replicated, unlike the hormonal claims.

Richest food sources

Creatine is found almost exclusively in animal foods, and the richest sources are red meat and fish: herring tops the list (around 0.65–1 g per 100 g), followed by pork, beef and salmon (roughly 0.4–0.5 g per 100 g), then tuna, cod and other white fish. Wild game such as venison is also high. Crucially, plant foods contain virtually none — which is exactly why vegetarians and vegans carry lower muscle creatine stores and tend to see the biggest, most noticeable benefit from supplementing. Even committed meat-eaters would need to eat over a kilogram of raw steak a day to match a 3–5 g supplement dose, and cooking destroys a portion of it — so food alone rarely saturates your stores the way a supplement does.

How much to take — and the safe ceiling

3–5 g of creatine monohydrate daily is all that's needed; a loading phase (20 g/day for a week) speeds saturation but isn't necessary. Skip 'HCl', 'buffered' and other premium forms — monohydrate is cheapest and best-evidenced. No formal upper limit applies at these everyday doses.

When and how to take it

Timing barely matters — take it whenever you'll remember, every day including rest days, to keep muscle stores topped up. With or without food is fine.

Too much / what to watch for

The only common effect is a little water held inside the muscle early on (not fat). A large single dose can cause stomach upset — split it or take with food. Major reviews (including the ISSN position stand) conclude creatine doesn't harm the kidneys or liver in healthy people; it does raise the blood creatinine lab marker without indicating damage — worth mentioning before a blood test.

What to stack with

Protein, magnesium, and effectively any other supplement — creatine is highly compatible.

What to avoid — supplements and medicines

Nothing of note for healthy people. With existing kidney disease or nephrotoxic medication, check with your doctor first.

Who should be cautious

People with pre-existing kidney disease should get medical advice. Otherwise creatine suits the vast majority of healthy adults — including older men, where it also helps preserve muscle.

Quality — what to look for on the label

Choose plain creatine monohydrate (Creapure is a well-regarded branded version) and skip marketing forms. Look for a single-ingredient product, third-party testing (Informed Sport, NSF) if you compete, and avoid proprietary blends that hide the actual creatine dose.

Bottom line

If you train, creatine is close to essential: safe, cheap and proven. It builds the muscle and capacity that support your hormones rather than raising testosterone directly — and the kidney and hair-loss fears don't hold up for healthy users.

Sources

van der Merwe et al., Clin J Sport Med (2009); Antonio et al., ISSN position stand, J Int Soc Sports Nutr (2021); Lak et al., hair-follicle RCT (2025); Mayo Clinic.

Chapter 10 · What Works
If you'd like to try it

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Based on guidance from the NHS, NICE, Cleveland Clinic and peer-reviewed research.

By M. Videika, author of The Testosterone Blueprint · Reviewed June 2026

General information, not a substitute for personal medical advice — always consult your doctor or a qualified health professional before making health decisions. If you are pregnant, breastfeeding, trying to conceive, under 18, or taking medication, speak to your doctor before starting any supplement.